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BBC has just launched a new home page at here - you can personalize every section on the site to match your interest, including color, position of any section. You can also add and remove your favorite sections the way you want, the where you want. However, layout can not be change from three columns to two columns. Currently, it is designed in three columns, with top story section merged in two columns.
What you can not do? You can not remove Top story section. Weather section can not be set for any of non-Britain location. Also, you may not be able to set your favorite stock price in business section. There are few more, may be you can add it in comment section <:-)
Overall it is beautifully designed and works well in latest Internet explorer and Fire fox
Via [BBC internet news blog]